The ruins of San Ignacio Mini, about 60 km from the capital, Posadas, is one of several examples of missionary remains, in southern Brazil, Paraguay, Uruguay and Brazil. It was founded in the early seventeenth century to evangelize the native Guarani area. These ruins were declared a World Heritage Site by UNESCO in 1984. This mission eventually grew to more than 4000 inhabitants, where the natives were taught trades and the Christian faith by the Jesuits. In 1631 most of these centres were besieged and destroyed, except this and a few more, and after the expulsion of the Jesuits in 1768 it was abandoned.
Ruins where the Quilmes Indians lived, if its birth was in 1666, its origins date from 1450 or 1480. Incas de Chile fleeing, settled in the valleys calchaquies (Tucuman, Argentina). then moved near the banks of touring silver walk over 1000 miles.